Abstract
This study aims at assessing the knowledge, attitudes and acceptance of platelet-rich fibrin (PRF) among 519 adult patients who attended the Department of Periodontics of university dental hospitals in Riyadh, Saudi Arabia from January to March 2019, using a self-administered, online questionnaire of 15 questions. Descriptive statistics including frequencies and percentages was calculated for data analysis. Less than half of the respondents have heard about the PRF procedure and knew its benefits (25% and 46%, respectively). Around 50% of the respondents thought that it accelerates wound healing and regeneration but it is painful, while 60% would agree to perform PRF procedure when needed but would not recommend it to others. Thus, increasing patients' level of knowledge and attitudes about PRF applications in dentistry is advisable. It is recommended to dentists to inform their patients about the safety and benefits of PRF, and to involve them in decision making.