Abstract
The oxidation of pyrazinamide by potassium permanganate in acidic media was studied spectrophotometrically at 525 nm. It was found to be zero order with respect to oxidant, fractional order with respect to hydrogen ion concentration and first order with respect to substrate. The average (Delta G#) was found to be 87.60 kJ mol(-1). The values Delta S# was found to be -0.2132 kJ mol(-1) and energy of activation was found to be 23.95 kJ mol(-1). A suitable mechanism is proposed based on the experimental conditions.