Abstract
Pseudo-first-order reaction rate for alkaline hydrolysis of 2-chloroquinoxaline (2-CQX) is carried out in acetonitrile (AN)-water (H2O) mixtures at 35 degrees C. Cationic surfactants as dodecyltrimethylammonium bromide (DOTAB) and an anionic surfactant as sodium dodecylsulphate (SDS) are used above their critical micelle concentration (cmc) to study the effect of micelles on reaction rate. When increasing the percentage of volume of AN, the rate profiles with DOTAB are shown to slightly increase with increasing surfactant concentration, while that with SDS are found to smoothly decrease. The micellar effect is explained in terms of a modified pseudo-phase ion exchange model. The binding constant (K-S) between 2-CQX and DOTAB as micelle showed a decrease by increasing percentage of volume of AN, while that with SDS increased. The counterion micellar coverage degrees () are found to be 0.55 and 0.85 with DOTAB and SDS systems, respectively, at all range of volume percentage of AN. Finally, the calculated ratio between rate constants in water to that in the micelle region k(w)/k(M) at different volume percentage of AN indicated that DOTAB enhances the reaction rate while SDS inhibits it.