Abstract
Current study involves laser-induced gold nanoparticles (GNPs) for breast cancer therapy. GNPs as a therapeutic agent using nanophotolysis approach are discussed. Coulomb explosion of GNPs is studied numerically using MATLAB. Our findings show that 8.40 x 10(20) ions are generated for short pulse laser interaction of 8 ns and laser irradiation of 2 J/cm(2) penetrates in the tumor depth of 3.30 cm. Cluster size of 98 nm produced 13.08 x 10(22) nanobullets that target the breast tumor. Short pulse laser of 2.27 ns generates maximum shock front velocity of 9.98 x 10(6) cm/s. Shock front of 20-146 mu m is produced for effectively damaging the breast cancer tissues. A total of 825 cells are damaged by 12.6 x 10(6) ions. Current results are matched with the literature and are in good correlation. Hence, we conclude that laser-irradiated GNPs using nanophotolysis approach are useful for targeted therapy of breast tumor.