Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses

Richard J. O'Connell; Michael R. Thon; Stephane Hacquard; Stefan G. Amyotte; Jochen Kleemann; Maria F. Torres; Ulrike Damm; Ester A. Buiate; Lynn Epstein; Noam Alkan; Janine Altmueller; Lucia Alvarado-Balderrama; Christopher A. Bauser; Christian Becker; Bruce W. Birren; Zehua Chen; Jaeyoung Choi; Jo Anne Crouch; Jonathan P. Duvick; Mark A. Farman; Pamela Gan; David Heiman; Bernard Henrissat; Richard J. Howard; Mehdi Kabbage; Christian Koch; Barbara Kracher; Yasuyuki Kubo; Audrey D. Law; Marc-Henri Lebrun; Yong-Hwan Lee; Itay Miyara; Neil Moore; Ulla Neumann; Karl Nordstroem; Daniel G. Panaccione; Ralph Panstruga; Michael Place; Robert H. Proctor; Dov Prusky; Gabriel Rech; Richard Reinhardt; Jeffrey A. Rollins; Steve Rounsley; Christopher L. Schardl; David C. Schwartz; Narmada Shenoy; Ken Shirasu; Usha R. Sikhakolli; Kurt Stueber; Serenella A. Sukno; James A. Sweigard; Yoshitaka Takano; Hiroyuki Takahara; Frances Trail; H. Charlotte van der Does; Lars M. Voll; Isa Will; Sarah Young; Qiandong Zeng; Jingze Zhang; Shiguo Zhou; Martin B. Dickman; Paul Schulze-Lefert; Emiel Ver Loren van Themaat; Li-Jun Ma; Lisa J. Vaillancourt

doi:10.1038/ng.2372

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Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses

Journal article

Peer reviewed

Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses

Richard J. O'Connell, Michael R. Thon, Stephane Hacquard, Stefan G. Amyotte, Jochen Kleemann, Maria F. Torres, Ulrike Damm, Ester A. Buiate, Lynn Epstein, Noam Alkan, …

Nature genetics, Vol.44(9), pp.1060-1065

01/09/2012

DOI: https://doi.org/10.1038/ng.2372

PMID: 22885923

Abstract

Genetics & Heredity

Life Sciences & Biomedicine

Science & Technology

Colletotrichum species are fungal pathogens that devastate crop plants worldwide. Host infection involves the differentiation of specialized cell types that are associated with penetration, growth inside living host cells (biotrophy) and tissue destruction (necrotrophy). We report here genome and transcriptome analyses of Colletotrichum higginsianum infecting Arabidopsis thaliana and Colletotrichum graminicola infecting maize. Comparative genomics showed that both fungi have large sets of pathogenicity-related genes, but families of genes encoding secreted effectors, pectin-degrading enzymes, secondary metabolism enzymes, transporters and peptidases are expanded in C. higginsianum. Genome-wide expression profiling revealed that these genes are transcribed in successive waves that are linked to pathogenic transitions: effectors and secondary metabolism enzymes are induced before penetration and during biotrophy, whereas most hydrolases and transporters are upregulated later, at the switch to necrotrophy. Our findings show that preinvasion perception of plant-derived signals substantially reprograms fungal gene expression and indicate previously unknown functions for particular fungal cell types.

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Title: Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses
Creators - without role: Richard J. O'Connell - Max Planck Institute for Plant Breeding Research
Michael R. Thon - Universidad de Salamanca
Stephane Hacquard - Max Planck Institute for Plant Breeding Research
Stefan G. Amyotte - University of Kentucky
Jochen Kleemann - Max Planck Institute for Plant Breeding Research
Maria F. Torres - University of Kentucky
Ulrike Damm - Westerdijk Fungal Biodiversity Institute
Ester A. Buiate - University of Kentucky
Lynn Epstein - Plant
Noam Alkan - Agricultural Research Organization
Janine Altmueller - University of Cologne
Lucia Alvarado-Balderrama - Broad Institute
Christopher A. Bauser - GATC Biotech
Christian Becker - University of Cologne
Bruce W. Birren - Broad Institute
Zehua Chen - Broad Institute
Jaeyoung Choi - Seoul Natl Univ, Ctr Fungal Genet Resources, Dept Agr Biotechnol, Seoul, South Korea
Jo Anne Crouch - Agricultural Research Service
Jonathan P. Duvick - Pioneer Hi-Bred
Mark A. Farman - University of Kentucky
Pamela Gan - RIKEN Center for Sustainable Resource Science
David Heiman - Broad Institute
Bernard Henrissat - Architecture et Fonction des Macromolécules Biologiques
Richard J. Howard - Pioneer Hi-Bred
Mehdi Kabbage - Texas A&M University
Christian Koch - Friedrich-Alexander-Universität Erlangen-Nürnberg
Barbara Kracher - Max Planck Institute for Plant Breeding Research
Yasuyuki Kubo - Kyoto Prefectural University
Audrey D. Law - University of Kentucky
Marc-Henri Lebrun - Biologie et Gestion des Risques en Agriculture
Yong-Hwan Lee - Seoul National University
Itay Miyara - Agricultural Research Organization
Neil Moore - University of Kentucky
Ulla Neumann - Max Planck Institute for Plant Breeding Research
Karl Nordstroem - Plant
Daniel G. Panaccione - West Virginia University
Ralph Panstruga - Max Planck Institute for Plant Breeding Research
Michael Place - University of Wisconsin–Madison
Robert H. Proctor - ARS, USDA, Natl Ctr Agr Utilizat Res, Peoria, IL USA
Dov Prusky - Agricultural Research Organization
Gabriel Rech - Universidad de Salamanca
Richard Reinhardt - Max
Jeffrey A. Rollins - Univ Florida, Dept Plant Pathol, Gainesville, FL 32611 USA
Steve Rounsley - Broad Institute
Christopher L. Schardl - University of Kentucky
David C. Schwartz - University of Wisconsin–Madison
Narmada Shenoy - Broad Institute
Ken Shirasu - RIKEN Center for Sustainable Resource Science
Usha R. Sikhakolli - Michigan State University
Kurt Stueber - Max
Serenella A. Sukno - Universidad de Salamanca
James A. Sweigard - Pioneer Hi-Bred
Yoshitaka Takano - Kyoto University
Hiroyuki Takahara - Max Planck Institute for Plant Breeding Research
Frances Trail - Michigan State University
H. Charlotte van der Does - University of Amsterdam
Lars M. Voll - Friedrich-Alexander-Universität Erlangen-Nürnberg
Isa Will - Max Planck Institute for Plant Breeding Research
Sarah Young - Broad Institute
Qiandong Zeng - Broad Institute
Jingze Zhang - Broad Institute
Shiguo Zhou - University of Wisconsin–Madison
Martin B. Dickman - Texas A&M University
Paul Schulze-Lefert - Max Planck Institute for Plant Breeding Research
Emiel Ver Loren van Themaat - Max Planck Institute for Plant Breeding Research
Li-Jun Ma - Broad Institute
Lisa J. Vaillancourt - University of Kentucky
Publication Details: Nature genetics, Vol.44(9), pp.1060-1065
Publisher: Springer Nature
Number of pages: 8
Grant note: Max Planck Society; Foundation CELLEX SPP1212; OC 104/1-3 / Deutsche Forschungsgemeinschaft; German Research Foundation (DFG) 2007-35600-17829 / US Department of Agriculture (USDA)-Cooperative State Research, Education and Extension Service (CSREES); United States Department of Agriculture (USDA); National Institute of Food and Agriculture 2009-34457-20125 / USDA-CSREES; United States Department of Agriculture (USDA); National Institute of Food and Agriculture AGL2008-03177/AGR; AGL2011-29446/AGR / Ministerio de Ciencia e Innovacion (MICINN) of Spain; Ministry of Science and Innovation, Spain (MICINN); Spanish Government University of Kentucky College of Agriculture Research Office Programme for Promotion of Basic and Applied Research for Innovations in Bio-oriented Industry
Identifiers: 9936535708331
Academic Unit: King Abdulaziz University
Language: English
Resource Type: Journal article