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Ligations of O-acyl threonine units to give native peptides via 5-, 8-, 9-and 10-membered cyclic transition states
Journal article   Open access  Peer reviewed

Ligations of O-acyl threonine units to give native peptides via 5-, 8-, 9-and 10-membered cyclic transition states

Siva S. Panda, Sumaira Liaqat, Anand D. Tiwari, Hadi M. Marwani, Hassan M. Faidallah, Abdul Rauf, C. Dennis Hall and Alan R. Katritzky
ARKIVOC free online journal of organic chemistry, Vol.2015(4), pp.9-18
19/09/2014
DOI: https://doi.org/10.3998/ark.5550190.p008.796

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
N-Acyl threonine isopeptides undergo acyl transfer in chemical ligations via 5-, 8-, 9- and 10-membered cyclic transition states to yield natural peptides, representing the first examples of successful isopeptide ligations from N-acyl threonine units.
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https://doi.org/10.3998/ark.5550190.p008.796View
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