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Liver cancer risk, coffee, and hepatitis C virus infection: a nested case-control study in Japan
Journal article   Open access  Peer reviewed

Liver cancer risk, coffee, and hepatitis C virus infection: a nested case-control study in Japan

K Wakai, Y Kurozawa, A Shibata, Y Fujita, K Kotani, I Ogimoto, M Naito, K Nishio, H Suzuki, T Yoshimura, …
British journal of cancer, Vol.97(3), pp.426-428
06/08/2007
DOI: https://doi.org/10.1038/sj.bjc.6603891
PMCID: PMC2360330
PMID: 17637681

Abstract

Adult Aged Case-Control Studies Coffee Hepatitis C - complications Humans Japan Liver Neoplasms - complications Middle Aged Risk Factors
We examined hepatocellular carcinoma mortality in relation to coffee consumption and anti-hepatitis C virus (HCV) antibody seropositivity in a nested case-control study involving 96 cases. The multivariate-adjusted odds ratios (95% confidence interval) for daily coffee drinkers vs non-drinkers were 0.49 (0.25-0.96), 0.31 (0.11-0.85), and 0.75 (0.29-1.92) in all cases, in HCV-positive and in HCV-negative individuals, respectively.
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