Abstract
Radiation-induced skin changes and dermatoses occur in the majority of patients receiving radiotherapy and may produce significant adverse effects. Radiation-induced acneiform eruption is a rare but likely an underreported cutaneous adverse effect. This is a case of a localized comedonal eruption induced by radiation therapy exposure in a 47-year-old male treated for a malignant tumor. Recognition and proper management of this presentation are important for the optimization of patient health, reassurance of the patient and the treating team, and avoidance of any unnecessary delays in surgical reconstruction planning.