Abstract
Patients with diabetes who are on maintenance renal hemodialysis (MRH) are generally inactive and can benefit from the aerobic exercise training (AET). To evaluate the effects of the twelve weeks AET program on functional capacity (FC) and hemodynamic parameters in those patients. 47-patients were randomly assigned into AET group (n=22) and control group (CG; n=25). Resting heart rate (RHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), the 6-minutes' walk test (6MWT) were all evaluated pre-study (evaluation-1), after 3-months (evaluation-2) and 2-months post-study cessation (evaluation-3). At evaluation-2; RHR, SBP, DBP, 6MWT mean values and percentages of changes were [75.41 +/- 2.77(-7.66%; P<0.05), 79.92 +/- 3.7(-0.14%; P=0.17)], [(138.42 +/- 1.65(-4.92%, P<0.05), 145.84 +/- 2.04(+0.15%; P=0.21)], [86.96 +/- 1.5(-6.64%; P<0.05), 92.76 +/- 1.3(-0.16%; P=0.86)], [443.73 +/- 21.04(+31.74; P<0.05), 337 +/- 12.23(-0.33%; P=0.3)] for the AET and the CG respectively. At evaluation-3; RHR, SBP, DBP, 6MWT mean values and percentages of changes were [78.5 +/- 3.08(+3.89%;P<0.05),80.24 +/- 3.26(-0.29%;P=0.16)],[(141 +/- 1.72(-3.14%<0.05), 145.8 +/- 1.87(+0.13%; P=0.45)], [89 +/- 1.31(-4.44%;P<0.05), 92.68 +/- 1.25(-0.25%; P=0.87)], [406.05 +/- 67.15 (+20.79; P<0.05), 337.24 +/- 11.31 (-0.25%; P= 0.32)] for AET and CG respectively.AET has extended favorable effects on RHR, SBP, DBP, and 6MWT in diabetic patients on MRH. Long-term application of a well-designed AET is advisable to prevent deterioration of the hemodynamic and functional capacity parameters.