Abstract
The use of microelectromechanical systems-based drug delivery vehicles is on the rise. These advancements in the technologies have enabled the researchers in developing miniaturized devices including drug delivery platforms. This has opened up a new arena in pharmaceutical research. The main advantage of these devices is their ability to control the release profile of the drugs in a temporal scale. The main components of the microelectromechanical systems-based drug delivery devices are the microsensors, microvalves, micropumps, microchannel and a miniaturized control system. The current review discusses the different pumping mechanisms and clinical applications of the microelectromechanical systems-based delivery devices.