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MIF promoter polymorphisms are associated with epiretinal membrane but not retinal detachment with PVR in an american population
Journal article   Peer reviewed

MIF promoter polymorphisms are associated with epiretinal membrane but not retinal detachment with PVR in an american population

Colleen M. Cebulla, William Stevenson, Heather Van Law, Tyler Heisler-Taylor, Sumaya Hamadmad, Mohd Hussain Shah, Bongsu Kim, Frederick H. Davidorf, Matthew Ohr, Michael Wells, …
Experimental eye research, Vol.185, pp.107667-107667
01/08/2019
DOI: https://doi.org/10.1016/j.exer.2019.05.007
PMID: 31108057

Abstract

ERM RD OR CI OVER-PVR Study Group MIF PVR
•MIF promoter polymorphisms rs5844572 and rs755622 are implicated in many inflammatory conditions.•Case-cohort genetic association study in the US from 2012 to 2018.•601 study subjects: RD (n = 180), RD with PVR (n = 120), ERM (n = 100) and 201 controls.•Significant association of rs755622 (C/C) and homozygous C7 haplotype with ERM.•No association was found between RD or PVR and the MIF polymorphisms.

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