Abstract
Sulfonamides are widely used in the treatment of many diseases due to their biological and pharmacological activities. In this paper, we prepared Cu(II) complex immobilized on the surface of magnetic Fe3O4 nanoparticles functionalized with 2-Pyridine Benzoimidazole ligand [MNPs@PBI-CuBr2] and its catalytic activity in the synthesis of N-aryl sulfonamides containing benzoxazole scaffolds through one-pot three-component reaction of 2-aminobenzoazoles, sulfonyl chloride and aryl iodides under ecofriendly conditions. The structure of the as-prepared MNPs@PBI-CuBr2 nanomaterial was well characterized by a number of spectroscopic techniques such as FTIR, SEM, EDX, TEM, XRD, TGA, VSM, MAP, XPS and ICP-OES. The MNPs@PBI-CuBr2 nanocatalyst was simply separated by magnetic separation and reused for seven times with constant activity. The TEM, XRD pattern and ICP-OES spectroscopy of catalyst after recycling were studied and the results were similar to before of utilization.