Abstract
Fabricating new biosensing constructs with high selectivity and sensitivity is the most needed environmental detection tool. In this context, several nanostructured materials have been envisaged to construct biosensors to achieve superior selectivity and sensitivity. Among them, MXene is regarded as the most promising to develop biosensors due to its fascinating attributes, like high surface area, excellent thermal resistance, good hydrophilicity, unique layered topology, high electrical conductivity, and environmentally–friendlier properties. MXenes-based materials have emerged as a prospective for catalysis, energy storage, electronics, and environmental sensing and remediation applications thanks to the above-mentioned exceptional characteristics. This review elaborates on the contemporary and state-of-the-art advancements in MXene-based electrochemical and biosensing tools to detect toxic elements, pharmaceutically active residues, and pesticide contaminants from environmental matrices. At first, the surface functionalization/modification of MXenes is discussed. Afterwards, a particular focus has been devoted to exploiting MXene to construct electrochemical (bio) sensors to detect various environmentally-related pollutants. Lastly, current challenges in this arena accompanied by potential solutions and directions are also outlined.
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•Surface functionalization/modification of MXenes.•Current development in MXene-based electrochemical biosensors.•Sensing and detection of toxic elements, pesticides, and pharmaceuticals.•Superior electrochemical performances of MXene-based sensing candidates.•Current challenges with potential solutions and future research opportunities.