Abstract
Anticancerous drugs have been produced by using heterocyclic compounds as prerequisites. However, it is high time to have an insight into developing inexpensive and less toxic nanocatalysts that can accelerate the formation of heterocyclic compounds for the treatment of cancer. Nanotechnology is an emerging field of science, nano -medicine uses nanoparticles to treat and diagnose diseased tissues in response to the continuing aspiration for more personalized medicine and new way of medical technologies. Considerable improvement has been achieved in producing magnetic nanoparticles with the appropriate sizes, morphologies, surface chemistry and chemical compositions. In this review, studies have been discussed to highlight the recent improvements in magnetic nanoparticles' application for the manufacturing of heterocyclic compounds as a promising drug to target as well as cause the apoptosis of cancer cells. The significance of nanocatalysts as diagnostic and therapeutic agent called as a theranostic tool for nanomedicine has been explored in contrast to the single treatment; utilization of nanocatalysts tends to be less toxic while carrying out therapeutic treatments such as chemotherapy and ther-motherapy or combined therapy. Nanomagnetic iron oxide has shown promising results as an outstanding carrier for cancer treatment, among other compounds. Coating and functionalization of magnetic nanoparticles can lead to qualities such as responsiveness to a particular trigger (such as pH or temperature), strong chemical stability and the capacity to localize to the tumour site. Moreover, the synthesis of magnetic nanoparticles as a contrast agents in drug delivery systems, chemodynamic therapy, magnetic resonance imaging and as a therapeutic component in tumor ablation therapy to induce cellular death have been surveyed. Finally, the challenges and future scope related to the clinical trials of magnetic nanoparticles as well as the nanocatalyst assisted in the formation of heterocyclic compounds have been addressed.