Abstract
During October 2007 a dairy cow serum collected after abortion tested positive to L. interrogans serovar Hardjo (serogroup Sejroe) with a titre of 1:400. After serological confirmation an official Outbreak was declared and restrictions measures were put in place (D.P.R. 320/54, O.M. 4 settembre 1985). The active control of the outbreak included direct prophylaxis measures, serological monitoring, molecular and microbiological diagnosis on urine samples collected from serologically positive animals. Antibiotic therapy was administered to positive animals. Based on this acquired experience, our study suggests ail alternative approach for reducing the period of sanitary and restriction measures.