Abstract
We proposed to elucidate the antidiabetic potential of Nephelium lappaceum (Rambutan) seed powder (peeled and unpeeled) by using in vitro bioassay. In this study, we investigated the antidiabetic potential of rambutan seed powder using in vitro glucose uptake mechanism by Saccharomyces cerevisiae (yeast). Rambutan seed powder (unpeeled) at a test concentration of 25 mg/mL was remarkable to enhance glucose uptake by yeast cells. In summary, rambutan seed powder found to possesses in vitro yeast glucose uptake enhancing potential.