Abstract
MgO polyhedral nanocages and nanocrystals, synthesized by non-catalytic simple thermal evaporation process, were used to fabricate high-sensitive amperometric glucose biosensor Which showed a high and reproducible sensitivity of 31.6 mu A mu M(-1) cm(-2) with a response time less than 5 s, linear dynamic range from 1.0 to 9.0 mu M and correlation coefficient of R = 0.9993. The detection limit of fabricated biosensor (based on SIN ratio = 3) was estimated to be 68.3 +/- 0.02 nM. To the best of our knowledge, this is the first report which demonstrates the use of MgO nanostructures for the fabrication of glucose biosensor; hence, this work opens a new way to utilize MgO nanostructures as all efficient electron mediator to fabricate efficient glucose biosensors. (c) 2009 Elsevier B.V. All rights reserved.