Microbial transformation of parthenolide

Ahmed M Galal; Abdel-Rahim S Ibrahim; Jaber S Mossa; Farouk S El-Feraly

doi:10.1016/S0031-9422(99)00066-7

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Microbial transformation of parthenolide

Journal article

Peer reviewed

Microbial transformation of parthenolide

Ahmed M Galal, Abdel-Rahim S Ibrahim, Jaber S Mossa and Farouk S El-Feraly

Phytochemistry (Oxford), Vol.51(6), pp.761-765

01/07/1999

DOI: https://doi.org/10.1016/S0031-9422(99)00066-7

Abstract

Asteraceae

Feverfew

Hydroxylation

Microbial

NMR

Parthenolide

Tanacetum parthenium

Transformation

Microbial transformation of the germacranolide parthenolide using Rhizopus nigricans, Streptomyces fulvissimus and Rhodotorula rubra yielded three new compounds: 11αH-dihydroparthenolide, 9β-hydroxy-11βH-dihydroparthenolide and 14-hydroxy-11βH-dihydroparthenolide. 11βH-dihydroparthenolide was the only common metabolite produced by all microorganisms.

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Details

Title: Microbial transformation of parthenolide
Creators - without role: Ahmed M Galal - King Saud University
Abdel-Rahim S Ibrahim - King Saud University
Jaber S Mossa - King Saud University
Farouk S El-Feraly - King Saud University
Publication Details: Phytochemistry (Oxford), Vol.51(6), pp.761-765
Publisher: Elsevier Ltd
Identifiers: 9953185108331
Academic Unit: King Saud University
Language: English
Resource Type: Journal article