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Microwave-assisted green approach toward the unexpected synthesis of pyrazole-4-carboxylates
Journal article   Peer reviewed

Microwave-assisted green approach toward the unexpected synthesis of pyrazole-4-carboxylates

Arshia, Syed Muhammad Saad, Shahnaz Perveen, Khalid Mohammed Khan and Wolfgang Voelter
Journal of the Iranian Chemical Society, Vol.13(8), pp.1405-1410
01/08/2016

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A practically efficient, environment friendly, and solvent free microwave-assisted protocol was developed for the synthesis of pyrazole-4-carboxylates. In this connection, we synthesized five new compounds (4a-4e) via microwave irradiation of a mixture of benzophenone hydrazones and acetoacetates in the absence of solvent. Short reaction time, easy workup and quantitative yield are the striking features of our protocol.

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