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Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities
Journal article   Peer reviewed

Microwave-assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities

Ali Bouattour, Mehdi Fakhfakh, Souhir Abid, Ludovic Paquin, Remy Le Guevel, Anne Corlu, Sandrine Ruchaud, Stephane Bach, Houcine Ammar and Jean-Pierre Bazureau
ARKIVOC free online journal of organic chemistry, pp.291-302
01/01/2017
DOI: https://doi.org/10.3998/ark.5550190.p010.C4C

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The synthesis of a series of new 4-imino-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thiones 6(a -f) without substituent in C-5 position using microwave dielectric heating is reported. These new compounds were obtained in three steps with good overall yields (21-50%). [GRAPHICS] .

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