Abstract
Mannich bases of 2-naphthol have the ability to chelate strongly to metal ions. Hence, they have great potential to be used as chiral catalysts, metallo-enzyme inhibitors and/or scavenger of heavy metal poisons. This paper deals with an efficient and expeditious microwave assisted-synthesis of novel bis-Mannich bases of 2-naphthols derived from aromatic aldehydes and diamines namely piperazine and N,N'-dialkylethylenediamines under solvent-free conditions. These compounds were also prepared under conventional reflux in ethanol. The compounds of this series displayed interesting NMR behaviour.