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Microwave irradiation: A facile, scalable and convenient method for synthesis of N-phthaloylamino acids
Journal article   Peer reviewed

Microwave irradiation: A facile, scalable and convenient method for synthesis of N-phthaloylamino acids

Hassan M. Al-Hazimi, Ayman El-Faham, Mohamed Ghazzali and Khalid Al-Farhan
Arabian journal of chemistry, Vol.5(3), pp.285-289
01/07/2012

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
We describe herein a fast and rapid technique for preparation of N-phthaloyl amino acids under microwave irradiation. The microwave methodology is rapid, convenient, proceeds under mild conditions, and gives a better yield (81-98%) and high purity of the title compounds. The spectral data as well as the X-ray analysis established the structure of the prepared N-protected amino acids. (C) 2012 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.

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