Moringa oleifera extract (Lam) attenuates Aluminium phosphide-induced acute cardiac toxicity in rats

Ahmed S. Gouda; Nagla A. El-Nabarawy; Samah F. Ibrahim

doi:10.1016/j.toxrep.2018.01.001

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Moringa oleifera extract (Lam) attenuates Aluminium phosphide-induced acute cardiac toxicity in rats

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Moringa oleifera extract (Lam) attenuates Aluminium phosphide-induced acute cardiac toxicity in rats

Ahmed S. Gouda, Nagla A. El-Nabarawy and Samah F. Ibrahim

Toxicology reports, Vol.5, pp.209-212

01/01/2018

DOI: https://doi.org/10.1016/j.toxrep.2018.01.001

PMCID: PMC5789123

PMID: 29387566

Abstract

AlP, aluminium phosphide

Aluminium phosphide

Cardiac toxicity

CAT, catalase

GR, glutathione reductase

Lam, moringa oleifera extract

MDA, malondialdehyde (product of lipid peroxidation)

Moringa oleifera extract

Oxidative stress

ROS, reactive oxidative stress

SOD, superoxid dismutase

Toxicity

• Aluminium phosphide (AlP) affects many organs especially heart. • Antioxidant activities of Moringa was investigated after acute AlP intoxication. • Moringa preventive effects were determined histopathologically. • Moringa significantly re-equilibrates antioxidant parameters back near to their normal values.

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Title: Moringa oleifera extract (Lam) attenuates Aluminium phosphide-induced acute cardiac toxicity in rats
Creators - without role: Ahmed S. Gouda - Princess Nourah bint Abdulrahman University
Nagla A. El-Nabarawy - Cairo University
Samah F. Ibrahim - Cairo University
Publication Details: Toxicology reports, Vol.5, pp.209-212
Publisher: Elsevier
Identifiers: 9928008208331
Academic Unit: Princess Nourah bint Abdulrahman University
Language: English
Resource Type: Journal article