Abstract
Chaetomiaceae fungi are ascosporulating fungi whose importance as human pathogens has been frequently ignored. In the current study, a new isolate of the genus
Subramaniula
was described. The fungus was isolated from the soil of Wadi Om Nefa’a, Hurghada in the Red Sea Governorate, Egypt. Previously,
Subramaniula
were misidentified as
Papulaspora
spp. According to molecular analysis, the fungus was identified as
Subramaniula asteroids
OP484336. Remarkably, this species has been found among other fungi responsible for keratitis in humans and has been recorded for the first time in Egypt. Analysing the
Subramaniula asteroids’
metabolic profile was one of the objectives of the current study because little is known about this family’s metabolome. The fungal extract’s untargeted metabolic profiling was carried out by gas chromatography-mass spectroscopy (GC/MS),
1
H and
1
H-HSQC nuclear magnetic resonance (NMR) data, and their corresponding databases. In total, fifty-nine metabolites have been reported in the polar and non-polar extracts. The majority of polar metabolites are amino acids and carbohydrates. The non-polar extract’s main components were 1-dodecanamine, N,N-dimethyl-, 1-tetradecanamine, N,N-dimethyl-, and 9-octadecenoic acid ethyl ester. The current study is the first to provide a metabolic profile of
Subramaniula asteroids
, which can be used in chemotaxonomical classification, antifungal drug development, and biological activity investigation of the studied species.