Abstract
A series of novel functionalized pyrano[2 ',3 ':4,5]pyrimido[1,6-b][1,2,4,5]triazaphosphinines have been synthesized by three-component reaction of 6-acetyl-3-amino-4-imino-7-methyl-5-phenyl-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine with aromatic aldehydes and dichloro(phenyl)phosphine in anhydrous THF. The proposed methodology is simple, efficient, and catalyst-free.