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Multimodal luminescent-magnetic boron nitride nanotubes@NaGdF₄:Eu structures for cancer therapy
Journal article   Peer reviewed

Multimodal luminescent-magnetic boron nitride nanotubes@NaGdF₄:Eu structures for cancer therapy

Xia Li, Nobutaka Hanagata, Xuebin Wang, Maho Yamaguchi, Wei Yi, Yoshio Bando and Dmitri Golberg
Chemical communications (Cambridge, England), Vol.50(33), pp.4371-4374
28/04/2014
DOI: https://doi.org/10.1039/c4cc00990h
PMID: 24643626

Abstract

Antineoplastic Agents - chemistry Antineoplastic Agents - therapeutic use Antineoplastic Agents - toxicity Boron Compounds - chemistry Cell Line, Tumor Cell Survival - drug effects Doxorubicin - chemistry Doxorubicin - therapeutic use Doxorubicin - toxicity Drug Carriers - chemistry Humans Magnetic Fields Nanostructures - chemistry Nanotubes - chemistry Neoplasms - drug therapy Neoplasms - radiotherapy
Boron nitride nanotubes@NaGdF4:Eu composites with core@shell structures were fabricated giving the opportunity to trace, target and thus to manipulate BNNTs in vitro. The composites show a significantly higher cellular uptake and chemotherapy drug intracellular delivery ability in the presence of an external magnetic field than that in its absence.

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