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Mutagenic Action of Phaseolinone, a Mycotoxin Isolated from Macrophomina phaseolina
Journal article   Open access

Mutagenic Action of Phaseolinone, a Mycotoxin Isolated from Macrophomina phaseolina

Gautam Bhattacharya, Tarun K Dhar, F Kathleen Bhattacharya, Kazi A I Siddiqui and Khursheed Siddiqui
Australian journal of biological sciences, Vol.40(4), pp.349-353
1987
DOI: https://doi.org/10.1071/BI9870349
PMID: 3330928

Abstract

Phaseolinone was mutagenic to excision-repair-deficient strains of Escherichia coli WP2 and also to Salmonella typhimurium TA100. The repair test was indicative of covalent binding of the toxin to DNA. The side-chain epoxide and the hydroxy groups of the molecule were found to be essential for mutagenic activity.
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https://doi.org/10.1071/BI9870349View
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