Sign in
Back
N-Pyridinyl Sulfilimines as a Source for alpha-Imino Gold Carbenes: Access to 2-Amino-Substituted N-Fused Imidazoles
Journal article   Peer reviewed

N-Pyridinyl Sulfilimines as a Source for alpha-Imino Gold Carbenes: Access to 2-Amino-Substituted N-Fused Imidazoles

Xianhai Tian, Lina Song, Matthias Rudolph, Qian Wang, Xinlong Song, Frank Rominger and A. Stephen K. Hashmi
Organic letters, Vol.21(6), pp.1598-1601
15/03/2019
DOI: https://doi.org/10.1021/acs.orglett.9b00140
PMID: 30807195

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Gold-catalyzed formal 1,3-dipolar annulation between readily accessible N-pyridinylsulfilimines and ynamides is reported. A diverse set of imidazole derivatives is prepared from the corresponding sulfilimines and ynamides. These functionalized cyclic products can undergo further transformations to afford diverse imidazole frameworks. Moreover, in situ synthesis is feasible and shows good potential in the synthesis of nucleoside analogues.

Metrics

1 Record Views

Details