Abstract
This work presents a microwave assisted solvent-free synthesis of N,N-dialkyl-4-aryl-3,4-dihydropyrimidinones/thiones in the presence of Ceric Ammonium Nitrate (CAN) via direct condensation of aromatic aldehydes, -keto ester, and N,N-dialkylurea/thiourea. The highlights of the methodology adopted are (i) facile condensation of the reactants into product without any side-products, and (ii) short reaction time with high yield and good purity. All the compounds synthesized were characterized and established by spectroscopic techniques such as FTIR, H-1 NMR, C-13 NMR, and Mass. The structure of the compound is further corroborated by single crystal X-ray diffraction analysis.