Abstract
In this report, copper (I) oxide (Cu2O) nanocatalyst was synthesized by chemically reducing a copper precursor with ascorbic acid (AA) and trisodium citrate (TSC) in alkali medium. The influence of Cu2O NPs on the developmental production of selenoquinoline derivatives (5a-c) under room temperature, thermal (80 degrees C), and different sonication conditions (power, irradiation time, catalyst loading, and other copper salts) was examined. The results indicated that increasing the ultrasonic power (300 W) for short time (60 min), the yield of seleno[2,3-b] quinoline derivatives (5a-c) improved to more than 95%. A proposed mechanism of this approach has been explained. Furthermore, the catalytic system can be recycled without affecting yields or reaction rates significantly. The main features of this protocol are the use of mild reaction conditions, no production of side products, easy work-up, and high yields. (C) 2021 Elsevier B.V. All rights reserved.