Abstract
COVID-19 is a respiratory disease caused by a newly identified coronavirus named severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since its inception in late December 2019, COVID-19 has led
to a tremendous loss of human life worldwide. To overcome the unprecedented challenges posed by the
COVID-19 pandemic to the public and economic health, strengthening the healthcare system is of utmost need.
In this regard, research communities are putting efforts into developing an advanced healthcare system that
could reduce the severe impacts of this pandemic. Nanotechnology is an advanced technology that has contributed
significantly to produce powerful arsenals for the frontline warriors in this battle against COVID-19. It has
offered opportunities for the development of fast and accurate point-of-care testing, efficient therapeutics and
vaccines, potent sanitizers, facemasks, and personal protective equipment against SARS-CoV-2. However, associated
toxicity, lengthy procedures of clinical trials, and uncertain health risks are some points that are still
debatable. The present paper provides an overview of COVID-19 specific therapeutics and vaccines with an
emphasis on nano-based strategies, which are significantly contributing towards the success of mitigation
measures and strategies against COVID-19. Furthermore, the associated challenges, current limitations, and opportunities
in this field are discussed.