Abstract
The chronic nature and associated
complications of nonhealing wounds have led to the emergence of nanotechnology-based
therapies that aim at facilitating the healing process and ultimately
repairing the injured tissue. A number of engineered nanotechnologies
have been proposed demonstrating unique properties and multiple functions
that address specific problems associated with wound repair mechanisms.
In this outlook, we highlight the most recently developed nanotechnology-based
therapeutic agents and assess the viability and efficacy of each treatment,
with emphasis on chronic cutaneous wounds. Herein we explore the unmet
needs and future directions of current technologies, while discussing
promising strategies that can advance the wound-healing field.
A myriad of advanced nanotechnology-driven therapies were designed
for targeting specific problems of chronic wound healing. The clinical
application of these therapies still requires intensive research for
the standardization of nanotechnologies.