Abstract
Arsenic is an element that raises much concern from the both environmental and human health. The effects of As on learning behavior, neurotransmitters, and oxidative stress indicators were studied in male Swiss white mice. The purpose of this study was to explore into the preliminary work described concerning memory, biochemical changes, and learning impairment in mice exposed to arsenic. The study results in the Shuttle box, Water-maze, T-Maze tests and body weight measurements, As-treated males demonstrated decreased body weight and learning behavior. Dopamine, DA, serotonin, 5-HA, and cholinesterase, AchE levels were all decreased. When compared to the control, GSH and the enzymes GST, CAT, and SOD activity were decreased, while TBARS was raised. This study concludes as the essential reasons that explain the causes of As influence on learning and other data, based on the results collected and other previous studies in this field. In general, additional research is required to determine As negative effects on various elements of human and animal health.