Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

Lara Kular; Maria Needhamsen; Milena Z. Adzemovic; Tatiana Kramarova; David Gomez-Cabrero; Ewoud Ewing; Eliane Piket; Jesper Tegnér; Stephan Beck; Fredrik Piehl; Lou Brundin; Maja Jagodic

doi:10.1186/s13148-019-0678-1

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Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

Journal article

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Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

Lara Kular, Maria Needhamsen, Milena Z. Adzemovic, Tatiana Kramarova, David Gomez-Cabrero, Ewoud Ewing, Eliane Piket, Jesper Tegnér, Stephan Beck, Fredrik Piehl, …

Clinical epigenetics, Vol.11(1), pp.86-86

30/05/2019

DOI: https://doi.org/10.1186/s13148-019-0678-1

PMCID: PMC6543588

PMID: 31146783

Abstract

Axonal guidance

CREB

DNA hydroxymethylation

DNA methylation

Multiple sclerosis

Neurodegeneration

Neurons

Synaptic plasticity

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Title: Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
Creators - without role: Lara Kular - Karolinska Institutet
Maria Needhamsen - Karolinska Institutet
Milena Z. Adzemovic - Karolinska Institutet
Tatiana Kramarova - Karolinska Institutet
David Gomez-Cabrero - Karolinska Institutet
Ewoud Ewing - Karolinska Institutet
Eliane Piket - Karolinska Institutet
Jesper Tegnér - Karolinska Institutet
Stephan Beck - University College London
Fredrik Piehl - Karolinska University Hospital
Lou Brundin - Karolinska Institutet
Maja Jagodic - Karolinska Institutet
Publication Details: Clinical epigenetics, Vol.11(1), pp.86-86
Publisher: BioMed Central
Grant note: ;
Identifiers: 9945381708331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article