Abstract
New Pd(II) and Pt(IV) triazine complexes [Pt
(
)
(Cl)
(H
O)
].3Cl.3H
O (
), [Pt
(
)
(Cl)
(H
O)
].3Cl (
), [Pt
(
)
(Cl)
(H
O)
].3Cl (
), [Pt
(
)
(Cl)
(H
O)
] .2Cl.4H
O (
), [Pd
(
)
(H
O)
] .3Cl
(
), [Pd
(
)
(H
O)
].3Cl
(
), [Pd
(
)
(H
O)
].3Cl
(
), and [Pd
(
)
(H
O)
].2Cl
(
) were synthesized and well characterized using elemental analyses, molar conductance, IR, UV-Vis, magnetic susceptibility,
H,
C-NMR spectra, and thermal analyses. These analyses deduced that the
,
, and
ligands act as tridentate forming octahedral geometry with Pt(IV) metal ions and square planar geometry in case of Pd(II) complexes but the
ligand acts as bidentate chelate. The molar conductance values refer to the fact that all the prepared s-triazine complexes have electrolyte properties which are investigated in DMSO solvent. Surface morphology behaviors of prepared complexes have been scanned using TEM. The crystalline behavior of triazine complexes has been checked based on X-ray powder diffraction patterns. The antimicrobial activity of the free ligands and their platinum(IV) and palladium(II) complexes against the species
(G+),
(G-),
, and
has been carried out and compared with the standard one. The coordination of ligands towards metal ions makes them stronger bacteriostatic agents, thus inhibiting the growth of bacteria and fungi more than the free ligands. The cytotoxic assessment IC
of the free ligands and its platinum(IV) complexes
against human colon and lung cancer cell lines introduced a promising efficiency.