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New Types of Mono and Bis Sulfonamides, Tosylamino Acids and Thiosulfonic Ester Derived from Xanthotoxin, Bergapten and Visnagin with Biological Interest
Journal article   Peer reviewed

New Types of Mono and Bis Sulfonamides, Tosylamino Acids and Thiosulfonic Ester Derived from Xanthotoxin, Bergapten and Visnagin with Biological Interest

A. M. Sh El-Sharief and S. Y. Al-Raqa
Phosphorus, sulfur, and silicon and the related elements, Vol.182(7), pp.1557-1580
01/07/2007

Abstract

Bergapten imidazolineiminothiones thiohydantoin tosylamino acids visnagin xanthotoxin
Xanthotoxin, bergapten, and visnagin sulfonyl chlorides have been reacted with diamines, hydrazine, amino acides, and imidazolidineiminothiones to produce the corresponding mono-, bis-sulfonamide, and tosylamino acid derivatives. Interaction of xanthotoxin-4-sulfonyl chloride with thiohydantoin furnished the respective thiosulfonic ester. The new products exhibited better antibacterial and antifungal activities.

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