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New bioactive macrocyclic diterpenoids from Jatropha multifida
Journal article   Peer reviewed

New bioactive macrocyclic diterpenoids from Jatropha multifida

Boddu Shashi Kanth, Avula Satya Kumar, Digambar Balaji Shinde, Kothapalli Hari Babu, Tuniki Venugopal Raju, Chityal Ganesh Kumar, Pombala Sujitha and Biswanath Das
Bioorganic & medicinal chemistry letters, Vol.21(22), pp.6808-6810
15/11/2011
PMID: 21996519

Abstract

Chemistry Chemistry, Medicinal Chemistry, Organic Life Sciences & Biomedicine Pharmacology & Pharmacy Physical Sciences Science & Technology
Two new macrocyclic diterpenoids, multifidanol (1) and multifidenol (2) along with several known compounds have been isolated from the stem of Jatropha multifida. The structures of the new compounds were established from the extensive studies of their 1D and 2D NMR spectra. The cytotoxic and antimicrobial activities of these two constituents were examined. (C) 2011 Elsevier Ltd. All rights reserved.

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