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New cadinene sesquiterpenoids from the Formosan soft coral Xenia puerto-galerae
Journal article   Peer reviewed

New cadinene sesquiterpenoids from the Formosan soft coral Xenia puerto-galerae

Chang-Yih Duh, Shih-Chao Chien, Pei-Ying Song, Shang-Kwei Wang, Ali Ali H El-Gamal and Chang-Feng Dai
Journal of natural products (Washington, D.C.), Vol.65(12), pp.1853-1856
01/12/2002
DOI: https://doi.org/10.1021/np0203281
PMID: 12502327

Abstract

Animals Anthozoa - chemistry Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Colonic Neoplasms Drug Screening Assays, Antitumor Humans Leukemia P388 Lung Neoplasms Methylene Chloride Mice Molecular Conformation Molecular Structure Nuclear Magnetic Resonance, Biomolecular Sesquiterpenes - chemistry Sesquiterpenes - isolation & purification Sesquiterpenes - pharmacology Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Taiwan Tumor Cells, Cultured - drug effects
Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia puerto-galerae. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

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