Abstract
WOS: 000088562000003
PubMed ID: 10924162
Four new caryophyllene derivatives- 14-hydroxy-4,5-dihydro-beta-caryophyllene (1), 14-acetoxy-4,5 -dihydro-beta-caryophyllene (2), 4,5-dihydro-beta-caryophyllene-14-al (3), and caryophylla-8(14)-en-5-one (4)-are reported from the essential oil of Betula litwinowii. Compounds 1-4 were characterized by MS and 1D and 2D NMR analyses and chemical transformations. The antibacterial and antifungal activity of 1 is also reported.