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New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity
Journal article   Peer reviewed

New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity

Abdul Majid Ayatollahi, Mustafa Ghanadian, M. Ahmed Mesaik, Omer Mohamed Abdella, Suleiman Afsharypuor, Farzad Kobarfard and Marjan Mirza-taheri
Journal of asian natural products research, Vol.12(12), pp.1020-1025
12/2010
PMID: 21128141

Abstract

10,18-dihydromyrinsol diterpenes Euphorbia aellenii immunomodulatory effect myrsinane
Two new 14-desoxo-10, 18-dihydromyrinsol diterpenoids (1 and 2) were isolated and characterized from the cytotoxic chloroform fraction of Euphorbia aellenii Rech. f. (Euphorbiaceae). The structures of the new compounds were elucidated by spectroscopic methods and their immunomodulatory properties were evaluated by T-cell proliferation and phagocyte chemiluminescence assays.

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