Abstract
The new synthesized supramolecular complexes (SC); [Cu-2(CN)(4)(Et3Sn)(2)(tbpe)], 1 and [Cu-2(CN)(3)(Et3Sn)(bpe)], 2 (tbpe=trans-1,2-bis(4-pyridyl)ethene and bpe=1,2-bis(4-pyridyl)ethane), were characterized by elemental analyses, electrical conductance, spectroscopic studies and thermal analyses. UV-Vis spectra and magnetic moment data suggested the tetrahedral geometry around Cu(I) atoms. The structures of the SC 1 and 2 were also theoretically studied using molecular mechanics (MM+). The structures were minimized with a semi-empirical (PM3) method. The organotin compounds represent significant advances in the clinical management of some cancer cell lines. 1 and 2 were tested as inhibitors and their citotoxicities showed potent growth inhibitory activity for hepatocellular carcinoma HePG-2, mammary gland breast cancer MCF-7, human prostate cancer PC3 and Colorectal carcinoma HCT-116 cell lines. The tested compounds showed high inhibitory anti-oxidant activity either using erythrocyte hemolysis or ABTS method.