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Nitriles in Organic Synthesis: A Convenient Route to Some Heterocycles Incorporating a Benzothiazole Moiety
Journal article   Peer reviewed

Nitriles in Organic Synthesis: A Convenient Route to Some Heterocycles Incorporating a Benzothiazole Moiety

M. E. A. Zaki, A. A. Fadda, K. Samir and F. A. Amer
Phosphorus, sulfur, and silicon and the related elements, Vol.181(8), pp.1815-1823
01/08/2006
DOI: https://doi.org/10.1080/10426500500542828

Abstract

2-cyanomethylbenzothiazole Benzothiazole chloroactyl chloride
2-(Benzo[d]thiazol-2-yl)-4-chloro-3-oxobutanenitrile (2) was utilized for the synthesis of several new benzothiazole derivatives. Compound 2 reacted with aniline, hydrazine hydrate, ethanolamine, and ethyl glycinate hydrochloride to yield benzothiazole derivatives 3-6, respectively.

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