Abstract
Cancer is presently one of the prominent causes of death in the world. Early cancer detection, which can improve the prognosis and survival of cancer patients, is challenging for radiologists. Low-dose computed tomography, a commonly used imaging test for screening lung cancer, has a risk of exposure of patients to ionizing radiations. Increased radiation exposure can cause lung cancer development. However, reduced radiation dose results in noisy LDCT images. Efficient preprocessing techniques with computer-aided diagnosis tools can remove noise from LDCT images. Such tools can increase the survival of lung cancer patients by an accurate delineation of the lung nodules. This study aims to develop a framework for preprocessing LDCT images. The authors propose a noise removal technique of discrete wavelet transforms with adaptive thresholding by computing the threshold with a genetic algorithm. The performance of the proposed technique is evaluated by comparing with mean, median, and Gaussian noise filters.