Novel Approach for the Synthesis of N-Substituted Pyrroles Starting Directly from Nitro Compounds in Water

Biswanath Das; Digambar Balaji Shinde; Boddu Shashi Kanth; Jayprakash Narayan Kumar

doi:10.1080/00397911.2010.526748

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Novel Approach for the Synthesis of N-Substituted Pyrroles Starting Directly from Nitro Compounds in Water

Journal article

Peer reviewed

Novel Approach for the Synthesis of N-Substituted Pyrroles Starting Directly from Nitro Compounds in Water

Biswanath Das, Digambar Balaji Shinde, Boddu Shashi Kanth and Jayprakash Narayan Kumar

Synthetic communications, Vol.42(4), pp.548-553

15/02/2012

DOI: https://doi.org/10.1080/00397911.2010.526748

Abstract

Aqueous HCl

indium

N-substituted pyrroles

nitro compound

Paal-Knorr reaction

A novel approach for a facile high-yielding synthesis of N-substituted pyrroles has been discovered by the treatment of nitroarenes with 2,5-dimethoxytetrahydrofuran using indium in dilute aqueous HCl at room temperature.

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Title: Novel Approach for the Synthesis of N-Substituted Pyrroles Starting Directly from Nitro Compounds in Water
Creators - without role: Biswanath Das - Indian Institute of Chemical Technology
Digambar Balaji Shinde - Indian Institute of Chemical Technology
Boddu Shashi Kanth - Indian Institute of Chemical Technology
Jayprakash Narayan Kumar - Indian Institute of Chemical Technology
Publication Details: Synthetic communications, Vol.42(4), pp.548-553
Publisher: Taylor & Francis Group
Identifiers: 9945063208331
Academic Unit: King Abdullah University of Science & Technology
Language: English
Resource Type: Journal article