Abstract
The synthesis of a novel series of quinazolinone derivatives 6-15 having the biologically active thioxo group utilizing 2-isothiocyanato-benzoic acid methyl ester 2 is reported. Their structures have been confirmed on the basis of elemental analyses and (IR,
1
H NMR, and mass) spectral data. Preliminary testing for the in vitro antitumor activity of some synthesized compounds against Ehrlich Ascities Carcinoma cells was carried out.