A combination of tetrachlorosilane and potassium cyanide (in situ trichlorosilyl cyanide) was found to work efficiently for hydrocyanation of ketones to afford the corresponding cyanohydrins in high yield under mild conditions.
Metrics
1 Record Views
Details
Title
Novel Uncatalyzed Hydrocyanation of Ketones utlizing Tetrachlorosilane-Potassium Cyanide Reagent