Novel series of dihydroquinolindihydro-spiro[indoline-3,6 '-[1,3]thiazine]-5 '-carbonitrile derivatives

Asmaa H. Mohamed; Mohammed B. Alshammari; Esmaat M. El-Sheref; Ashraf A. Aly

doi:10.1016/j.molstruc.2020.128618

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Novel series of dihydroquinolindihydro-spiro[indoline-3,6 '-[1,3]thiazine]-5 '-carbonitrile derivatives

Journal article

Peer reviewed

Novel series of dihydroquinolindihydro-spiro[indoline-3,6 '-[1,3]thiazine]-5 '-carbonitrile derivatives

Asmaa H. Mohamed, Mohammed B. Alshammari, Esmaat M. El-Sheref and Ashraf A. Aly

Journal of molecular structure, Vol.1219, p.128618

05/11/2020

DOI: https://doi.org/10.1016/j.molstruc.2020.128618

Abstract

Chemistry

Chemistry, Physical

Physical Sciences

Science & Technology

A series of new spiro[indoline-3,6'-[1,3]thiazines] were synthesized in modest yields by refluxing of substituted (1,2-dihydroquinolin-3-yl)-methylene)hydrazinecarbothioamides with 2-(2-oxoindolin-3-ylidene)malononitrile in pyridine as a solvent. The structure assignment of all obtained products has been confirmed by H-1, C-13 NMR, 2D-NMR, N-15 NMR spectroscopy in addition to elemental analyses. The possible mechanism for the reaction is also discussed. (C) 2020 Published by Elsevier B.V.

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Title: Novel series of dihydroquinolindihydro-spiro[indoline-3,6 '-[1,3]thiazine]-5 '-carbonitrile derivatives
Creators - without role: Asmaa H. Mohamed - Minia University
Mohammed B. Alshammari - Prince Sattam Bin Abdulaziz University
Esmaat M. El-Sheref - Minia University
Ashraf A. Aly - Minia University
Publication Details: Journal of molecular structure, Vol.1219, p.128618
Publisher: Elsevier
Number of pages: 7
Grant note: No10302/1/2019 / Deanship of Scientific Research at Prince Sattam Bin Abdulaziz University, Saudi Arabia
Identifiers: 9926042208331
Academic Unit: Prince Sattam Bin Abdulaziz University
Language: English
Resource Type: Journal article