Novel tetralone-derived retinoic acid metabolism blocking agents : Synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays

SOOK WAH Yee; Laetitia Jarno; Claire Simons; MOHAMED SAYED Gomaa; Carole Elford; Li-Ling Ooi; Michael P Coogan; Richard Mcclelland; Robert Ian Nicholson; Bronwen A. J Evans; Andrea Brancale

doi:10.1021/jm0501681

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Novel tetralone-derived retinoic acid metabolism blocking agents : Synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays

Journal article

Peer reviewed

Novel tetralone-derived retinoic acid metabolism blocking agents : Synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays

SOOK WAH Yee, Laetitia Jarno, Claire Simons, MOHAMED SAYED Gomaa, Carole Elford, Li-Ling Ooi, Michael P Coogan, Richard Mcclelland, Robert Ian Nicholson, Bronwen A. J Evans, …

Journal of medicinal chemistry, Vol.48(23), pp.7123-7131

17/11/2005

DOI: https://doi.org/10.1021/jm0501681

PMID: 16279770

Abstract

Biological and medical sciences

Medical sciences

Miscellaneous

Pharmacology. Drug treatments

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Title: Novel tetralone-derived retinoic acid metabolism blocking agents : Synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays
Creators - without role: SOOK WAH Yee - Cardiff University
Laetitia Jarno - Cardiff University
Claire Simons - Cardiff University
MOHAMED SAYED Gomaa - Cardiff University
Carole Elford - Cardiff University
Li-Ling Ooi - Cardiff University
Michael P Coogan - Cardiff University
Richard Mcclelland - Cardiff University
Robert Ian Nicholson - Cardiff University
Bronwen A. J Evans - Cardiff University
Andrea Brancale - Cardiff University
Publication Details: Journal of medicinal chemistry, Vol.48(23), pp.7123-7131
Publisher: American Chemical Society
Identifiers: 9915530808331
Academic Unit: Imam Abdulrahman Bin Faisal University
Language: English
Resource Type: Journal article