Abstract
Background: Vesicoureteral reflux (VUR) classified as a congenital anomaly of the kidney and urinary tract and the most frequent among the pediatric population .VUR is the backflow of the urine from the bladder up into the ureter and the kidney .The complication of the disease could result in recurrent urinary tract infections (UTI) , hypertension, and renal scarring. Which may further progress, ending up with permanent kidney damage The aim of this study is to further explore the natural history of the disease, management, and the long-term sequelae of VUR in the pediatric population in King Abdulaziz University Hospital, Jeddah.
Methods: Retrospective cohort study, this study was approved by the research ethics committee of King Abdulaziz University hospital from January 2010 to July 2017.A retrospective review was conducted on the records of pediatric patients diagnosed with Vesicoureteral reflux (VUR) either primary and secondary ages 0-18. The diagnosis of VUR was based upon the demonstration of reflux of urine from the bladder into the upper urinary tract by con-trast voiding cystourethrogram (VCUG).
Results: Among the103 patients assessed, 74 (71.8%) were males, The mean age at the time of diagnosis was 2.2 (+/- 3.1) years, and 63 (63.6%) were diagnosed at the first year of their life . There were no significant associations in the distribution of VUR outcomes by gender or age at diagnosis . The grades of VUR before and after surgery, where grade 5 reduced significantly from 54.2% before surgery to only 12.2% after surgery, p-value < 0.05.
Conculsion: This study found that male patients have a higher prevalence of VUR than females. And most of the patients diagnosed at the first year of their life.
UTI is more frequent among patients with CKD and unresolved VUR. Furthermore, antireflux surgery resulted in decrease the severity of VUR