Abstract
A new and efficient one-pot preparation of substituted iminium perchlorate heterocycles 3a-e by cyclocondensation of binucleophiles with symmetrical vinamidinium salt A has been achieved. Their structures were characterized by spectral (nuclear magnetic resonance and infrared) and elemental analytical data. Using the disc diffusion strategy against Gram-positive and Gram-negative microscopic organisms, the antimicrobial movement of the synthesized iminium perchlorate heterocycles 3a-e was estimated. The results showed that iminium perchlorate heterocycles are effective against Salmonella typhimurium, Listeria monocytogenes, and Micrococcus luteus with moderate to high activity, and their minimum inhibitory concentrations ranging from 0.0024 to 1.25 mg/ml. Moreover, these compounds exhibited significant antioxidant activities.
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